Table 2.

Human neutrophil lipocalin.a,b

  • Produced by human neutrophils and epithelial cells

  • Stored as a preformed molecule in secondary (specific) granules

  • Production induced in epithelial cells by, e.g., TNF-α

  • Homology with other lipocalins

  • Siderophore, mediates apoptosis

  • Binds gelatinase B(MMP-9)

  • Monomer 22 kDa, homodimer 45 kDa, heteromer >90 kDa

  • a Also called neutrophil gelatinase-associated lipocalin (NGAL) or lipocalin 2 (LCN2).

  • b The table was modified from reference (4) with permission.