Table 2.

Summary of causative agents of BSIs, based on patient population, each reported as a percentage of total.

PathogenNosocomial BSI in 24179 adult patients from national surveillance study, % (26)aBSI in 1470 adult patients from 9 US community hospital, % (64)cCommunity-acquired bacterial BSI in 1158 (+) cultures from adult HIV+ patients, US and Europe, % (65)Nosocomial BSI in 2340 adult oncologic patients, US, % (66)dBSI in 1484 newborn infants, US, % (67)
Gram positive
    S. aureus20.228.319.611.53.5
    Other Staphylococcus species31.39.87.330.2
    Enterococcus species9.43.42.911.63.1
    Streptococcus speciesSee footnoteb4.8S. pneumoniae: 22.86.0S. agalactiae: 35.8
Other: 7.8Viridans group: 18.9
Group D: 1.4
S. pneumoniae: 0.9
    OtherRhodococcus equi: 0.91.2Listeria monocytogenes: 1.3
Gram negative
    E. coli5.623.710.57.624.8
    Klebsiella species4.86.61.26.40.9
    Enterobacter species3.92.02.63.0
    Serratia species1.70.9
    Pseudomonas species4.33.47.14.4
    Acinetobacter species1.30.71.5
    OtherProteus spp.: 3.8Salmonella spp.: 12.43.2H. influenzae: 4.5
Citrobacter spp.: 0.7H. influenzae: 2.5
Campylobacter spp.: 1.5
Anaerobes1.30.93.4
Fungi
    Candida species9.00.7Not reviewed8.5
Polymicrobial13.24.1Not reviewed14.11.6
  • a Except for anaerobes and polymicrobial BSI, percentages given are for monomicrobial episodes (n = 20978).

  • b Composite data not provided; viridans group streptococci accounted for 0.5% of nonneutropenic patients and 2.0% of neutropenic patients.

  • c Except for polymicrobial BSI, percentages given are for all isolates (n = 1514).

  • d Except for polymicrobial BSI, percentages given are for all isolates (n = 2711).