Table 2.

Univariate and multivariate analyses of analytical serum parameters.

Univariate analysisMultivariate analysis
HR (95%CI)pHR (95%CI)pHR (95%CI)p
Abnormal FLCa ratio2.2 (0.7–7.2)0.182
Non-IgG MGUS0.5 (0.1–1.9)0.313
M-Ig > 1.5g/dL8.3 (2.9–24.3)<0.0017.0 (2.3–21.4)0.001
HLC Ig'κ /Ig'λ2.4 (0.9–6.7)0.089
iHLC > 1.5g/dL8.7 (2.7–28)0.0015.9 (2.0–17.5)0.001
IMIb1.1 (0.4–3.2)0.790
Severe IMI3.2 (1.1–9.5)0.0243.1 (1.0–9.5)0.0461.9 (0.6–6.2)0.261
Severe IPc1.8 (0.3–9.3)0.480
  • Bold p values represent statistically significant results.

  • a FLC stands for free light chain.

  • b IMI stands for isotype-matched immunosuppression.

  • c IP stands for classical immunoparesis.